Next generation sequencing (NGS) is a revolutionary technology that simultaneously adds nucleotides while copying a DNA strand. This process generates a signal corresponding to the nucleotide type and position of the growing DNA strand, enabling efficient DNA sequencing.
Our next generation sequencing services include standard and custom options for extraction, library preparation, sequencing, and bioinformatics. All our NGS services are performed at our state-of-the-art laboratory in New Jersey using the latest NGS technologies, including the new Illumina® NovaSeq® X series and PacBio® Revio™ platforms, to ensure you receive the highest quality data. Our Ph.D.-level scientists provide free consultations, real-time updates, and post-delivery assistance — supporting you throughout each step of your project.
As fellow scientists and genomics leaders, we continuously optimize our processes to deliver the best results that meet your budget and deadline. Whether it’s your first NGS project or your hundredth, we are committed to helping you find the next generation sequencing service that aligns with your research needs.
Next Generation Sequencing (NGS) is a technology in which nucleotides are added in parallel to the copying of a DNA strand. When nucleotides are incorporated into the growing DNA strand, a signal is generated that corresponds to the nucleotide type and position. Regardless of the distinct method used to capture nucleotide information, NGS provides a wide snapshot of the genome of interest with higher sensitivity and higher capacity with sample multiplexing.
There are several distinct methods used to generate and capture signals that translate into a DNA sequence.
NGS is important for any molecular biologist because of its speed. With the ability to sequence millions of DNA strands simultaneously in a single run, the fast turnaround time allows for high sample volumes and the ability to sequence up to thousands of genes or gene regions. NGS technology enables the scientist to expand their DNA snapshot – gaining a wider perspective and understanding with comprehensive genomic coverage of their sample.
NGS sequences millions to billions of DNA fragments in parallel, allowing for significantly high-throughput and rapid, cost-effective generation of genomic data. Sanger sequencing traditionally produces longer read lengths than NGS, at lower throughput since DNA fragments are read one at a time. Sanger sequencing is advantageous for certain applications, such as validating DNA clones, sequencing long stretches of DNA, and resolving complex genomic regions.
For information on our NGS platforms as well as recommended configurations of your projects, please visit the NGS Platforms page. Azenta does not guarantee data output or quality for sequencing-only projects.